Brazil's 17-match unbeaten run has come to an end.
The Copa America winners were beaten 1-0 by Peru in an international friendly in Los Angeles.
Elsewhere, Uruguay and the USA played out a 1-1 draw while Argentina thrashed Mexico 4-0.
Wednesday's other international friendlies saw Honduras beat Chile 2-1, Ecuador getting the better of Bolivia 3-0 and Colombia playing out a goalless draw with Venezuela.