Bharat Biotech's homegrown COVID-19 vaccine has shown an interim vaccine efficacy of 81% in late-stage clinical trials, the Indian company said on Wednesday.
The interim analysis was based on 43 recorded cases of COVID-19 in the trial of 25,800 participants, conducted in partnership with the Indian government's medical research body.
Thirty-six of the 43 cases were recorded in participants who received a placebo, compared with seven cases in people who were given the Bharat Biotech vaccine, pointing to an efficacy rate of 80.6%, the company said.
India had approved the vaccine, branded COVAXIN, in January without late-stage efficacy data, raising questions about its effectiveness.
India's vaccination drive, currently underway, includes COVAXIN and a vaccine developed by Oxford University and AstraZeneca.
Earlier this week, Indian Prime Minister Narendra Modi was inoculated with the first dose of COVAXIN.
At least 12 people were killed and three others abducted when gunmen attacked a mining site in Atoso village in Nigeria's restive Plateau state, a local group leader said on Wednesday.
The United Nations and aid groups have warned on Wednesday that humanitarian operations in the Palestinian territories, particularly Gaza, were at risk of collapse if Israel does not lift impediments that include a "vague, arbitrary, and highly politicised" registration process.
Israel has approved a deal that will supply natural gas to Egypt, Israeli Prime Minister Benjamin Netanyahu said on Wednesday, describing it as the country's largest-ever gas deal.
The United States has approved $11.1 billion in arms sales to Taiwan on Wednesday, the largest ever US weapons package for the island which is under increasing military pressure from China.
President Donald Trump has expanded a list of countries subject to a full travel ban on Tuesday, prohibiting citizens from an additional seven countries, including passports from Syria and Palestine, from entering the United States.