Bharat Biotech's homegrown COVID-19 vaccine has shown an interim vaccine efficacy of 81% in late-stage clinical trials, the Indian company said on Wednesday.
The interim analysis was based on 43 recorded cases of COVID-19 in the trial of 25,800 participants, conducted in partnership with the Indian government's medical research body.
Thirty-six of the 43 cases were recorded in participants who received a placebo, compared with seven cases in people who were given the Bharat Biotech vaccine, pointing to an efficacy rate of 80.6%, the company said.
India had approved the vaccine, branded COVAXIN, in January without late-stage efficacy data, raising questions about its effectiveness.
India's vaccination drive, currently underway, includes COVAXIN and a vaccine developed by Oxford University and AstraZeneca.
Earlier this week, Indian Prime Minister Narendra Modi was inoculated with the first dose of COVAXIN.
Russian forces staged their largest ever drone attack on Ukraine overnight, cutting power to much of the western region of Ternopil and damaging residential buildings in Kyiv region, Ukraine's officials said on Tuesday.
Israeli strikes pummelled south Beirut on Monday, Lebanese official media said, while health authorities reported 31 people killed across the country, most of them in the south.
At least one police officer was killed and dozens of people injured in Pakistan as supporters of jailed former Prime Minister Imran Khan clashed with security forces outside the capital Islamabad on Monday, officials and Khan's party said.
A small plane travelling to Costa Rica's capital of San Jose crashed on Monday afternoon, authorities said, killing five of the six passengers on board.
Sectarian fighting in northwestern Pakistan which killed more than 80 people last week restarted on Monday, officials said, breaching a seven-day brokered ceasefire.